Engine Biosciences

Others · HealthTech · Series A

AI and high-throughput genomics platform for target discovery and precision oncology

About

Engine Biosciences is a venture-backed biotechnology company pioneering network biology and precision medicine. The platform integrates high-throughput combinatorial CRISPR wet-lab experimentation with machine learning algorithms (NetRx and CombiGEM) to map complex gene interactions, discover novel synthetic lethality targets, and develop precision oncology therapeutics.

Founded

2014 (Incorporated 2018)

Total Funding

$86M+ ($93.6M total commitments)

Key Investors

Polaris Partners, ClavystBio, EDBI, Coronet Ventures, SEEDS Capital, Invus, 6 Dimensions Capital, Baidu Ventures, WuXi AppTec

Core Platforms

NetRx (Machine Learning / Biological Network Analysis) & CombiGEM (Massively parallel combinatorial genetic screening)

Therapeutic Focus

Precision oncology targeting high-unmet-need cancers (ovarian, colorectal, liver, breast)

Dual Global HQs

Singapore (160 Robinson Road) & San Carlos / San Francisco, California, USA

Team

Jeffrey Lu(Co-founder & CEO)

Timothy Lu(Scientific Co-founder)

Jim Collins(Scientific Co-founder)

Prashant Mali(Scientific Co-founder)

Office

Directions

Hyderabad, Telangana, India (Engineering & Computational Biology Network)

loading map pinpoint…